Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4)-MMAE Size:1mg lysis and gap-junctional communication and

lysis and gap-junctional communication and to detect changes in cell or liposome volume

Linker substitution influences succinimide ring hydrolysis equilibrium impacting the stability of attachment to antibody-drug conjugates

664 SMILES NCCOCCOCCOCCNC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name CP-Tetrazine Synonyms SNAP2-Tetrazine CAS Number Related CAS Molecular Formula C23H21ClN8O2 Molecular Weight 476

Product Name Indisulam Synonyms CAS Number 165668-41-7 Related CAS Molecular Formula C14H12ClN3O4S2 Molecular Weight 385

Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4)-MMAE Size:1mg lysis and gap-junctional communication andSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly